Texans starting tight end Pharaoh Brown was ruled out for the second consecutive game due to a hamstring injury sustained a week ago at practice.
Brown has 12 catches for 114 yards on 18 targets.
Rookie tight end Brevin Jordan caught his first NFL touchdown pass during his regular-season debut against Los Angeles.
The Texans also ruled out starting linebacker Christian Kirksey, who has a fractured thumb and ligament damage, and didn't practice all week after starting against the Rams and saying Monday he didn't know how long he will play in a protective club.
Kirksey is the Texans' leading tackler with 56 tackles and has one interception.
Veteran linebacker Kevin Pierre-Louis was upgraded to full participation from an illness.
The Texans have Kamu Grugier-Hill, Pierre-Louis and Zach Cunningham and Neville Hewitt to fill in at linebacker, also claiming linebacker Eric Wilson off waivers from the Philadelphia Eagles.
The Texans also ruled out linebacker Hardy Nickerson due to a concussion and Pro Bowl quarterback Deshaun Watson for the ninth consecutive game due to non-injury reasons-personal matter.