Texans veteran running back David Johnson's hard-luck season took another turn Monday.
He was placed on the reserve-COVID-19 list along with linebacker Neville Hewitt and fullback-tight end Paul Quessenberry.
Johnson missed Sunday's game against the Los Angeles Chargers due to a quadriceps injury.
In his place, running back Rex Burkhead rushed for a career-high 149 yards and two touchdowns.
Johnson has rushed for 200 yards on 62 carries and has 29 catches for 217 yards and one touchdown
Hewitt has been starting at linebacker with Christian Kirksey and Kamu Grugier-Hill on the reserve-COVID-19 list, Kirksey was activated Saturday and played Sunday.
Quessenberry played in Sunday's game.
The Texans now have the following players on the reserve-COVID-19 list: Johnson, Hewitt, Quessenberry, linebacker Tae Davis, center Justin Britt, left tackle Tytus Howard, left guard Lane Taylor, defensive linemen Jon Greenard, Jordan Jenkins, Roy Lopez, Jaleel Johnson, Derek Rivers Maliek Collins, wide receiver Brandin Cooks, kicker Ka'imi Fairbairn, linebacker Kamu Grugier Hill, safeties Eric Murray and A.J. Moore, linebacker Eric Wilson and cornerback Cre'Von LeBlanc.