Texans Pro Bowl running back Dameon Pierce didn't practice Wednesday and his status is regarded as day-to-day due to a sprained ankle.

Joe Mixon’s injury isn’t regarded as long term, but it’s increasingly likely he may be sidelined for Sunday’s game against the Minnesota Vikings.

Backup running back Cam Akers took the first-team snaps Wednesday with running back Dameon Pierce sidelined with a mild strained hamstring that kept him out of the Chicago game. Pierce is regarded as close to returning, per a league source.

Meanwhile, starting center Juice Scruggs and backup center Jarrett Patterson worked out on the side with trainers. Scruggs, who missed the Chicago game with a groin injury, is expected to return this week, barring a setback. The Texans signed center Scott Quessenberry to the practice squad and have Kendrick Green to step in if Scruggs and Patterson are unavailable.

The Texans have reviewed video of the play and regard Bears linebacker T.J. Edwards’ hit as an illegal hip-drop tackle, which was outlawed by the NFL due to a high rate of injury. Now, the Texans are submitting the play to the league office for review. Edwards could be subject to a $16,883 fine from the NFL, if it’s his first offense. A second violation results in a $22,511 fine.

Mixon left the Texans’ 19-13 win under his own power, limping into the blue medical tent before going to the locker room briefly for more examination. Mixon had a magnetic resonance imaging exam Monday, which revealed no structural damage.

“With the tackle, in my mind, it is definitely considered the hip drop when a defender unweights himself, and he puts all his weight on the runner’s legs,” Texans coach DeMeco Ryans said during his weekly Monday press conference at NRG Stadium. “You see why we want to get the hip-drop tackle out of the game because it causes a lot of injuries when it happens. The hip-drop tackle doesn’t happen much, but the percentage of injury when it does happen is very high and you saw that there with Joe and his ankle.

“The defender landed on his ankle. So, tough spot to be in. We all want to coach it better on defenders. That is why you want to put your body in front and tackle guys in front and not reaching from behind, and the defender is in a bad spot there. He’s trying to get Joe down and the only way when you’re in a bad spot, the only way, is to unweight yourself and you put your weight off on his leg. So, unfortunate that that happened to Joe.”

Mixon, who rushed for one yard on one carry before being taken back out of the game and replaced by Cam Akers, who rushed for a team-high 32 yards on seven carries and lost a fumble on an unflagged helmet-to-helmet shot in the red zone, finished the game with nine carries for 25 yards. He caught three passes for 25 yards one week after rushing for 159 yards and a touchdown on a career-high 30 carries.

“The NFL and NFLPA made it a rule and an emphasis for a reason,” Mixon wrote on social media after the game. “Time to put your money where your mouth is. When I got up, I asked the ref where is the flag that was a hip tackle. & his reply was no it wasn’t.”

The Texans rushed for just 3.4 yards per carry, gaining 75 yards on 22 carries one week after Mixon averaged 5.3 yards per run against the Colts.

“Losing Joe was tough for our offense,” Ryans said. “The production that Joe had the first week was beneficial. He was key to our success in the first week.”

Ryans was noncommittal on Mixon’s status for Sunday’s road game at Minnesota.

It’s unclear if Mixon will be able to play this week.

“We’ll see on the injury,” Ryans said. “We’ll see. We’ll evaluate Joe as we go throughout the week. Just take it day by day.”

Aaron Wilson is a contributor to Sports Talk 790.